反应详情

A mixture of 9.5 parts of α-(aminomethyl)-m-chlorobenzyl alcohol, 7.15 parts of 2-(nitramino)-2-imidazoline and 40 parts of xylene is stirred in an oil-bath at 150°-160°C. while a great part of the xylene is distilled off. The resulting residue is diluted with a few parts of acetone and the product is allowed to crystallize. It is filtered off and crystallized from 4-methyl-2-pentanone, yielding m-chloro-α-(2-imidazolin-2-ylaminomethy)benzyl alcohol; m.p. 108.5°C.

1. distillationis distilled off
2. additionThe resulting residue is diluted with a few parts of acetone
3. customto crystallize
4. filtrationIt is filtered off
5. customcrystallized from 4-methyl-2-pentanone