Ethyl 4-(phenylmethoxy)benzoate → Sodium 4-carboxyphenoxy phenyl methane

HRID 1576919Notes

Reaction equation

HRID 1576919 reaction equation
C([O:3][C:4]([C:6]1[CH:19]=[CH:18][C:9]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:8][CH:7]=1)=[O:5])C.[Na:20]>C(O)C.[OH-].[Na+]>[C:4]([C:6]1[CH:19]=[CH:18][C:9]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:8][CH:7]=1)([OH:5])=[O:3].[Na:20]

Participants

5

Reactant 2

HCID 191414Ethyl 4-(phenylmethoxy)benzoateHCID 5360545Sodium

Product 1

HCID 70551218Sodium 4-carboxyphenoxy phenyl methane

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

To a solution of 4-ethoxycarbonylphenoxy phenyl methane (6.3g) in ethanol (30ml), sodium hydroxide solution (70ml.; 10N) was added and the mixture boiled under reflux with vigorous stirring for 18 hr. After cooling the sodium salt was filtered off and dried, m.p. >340°.

Workup

  1. temperatureunder reflux
  2. filtrationwas filtered off
  3. customdried

Sources & evidence

ORD record
ord-1781cb96797f463eb6077f085c844805
Source dataset
uspto-grants-1976_09
Patent number
US03983164

Reaction notes

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