Thionyl Chloride → 4-Benzyloxybenzoylchloride

HRID 1576923Notes

Reaction equation

HRID 1576923 reaction equation
[C:1]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)(O)=[O:2].S(Cl)([Cl:20])=O>>[Cl:20][C:1]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[CH:6][CH:5]=1)=[O:2]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 738804-(Benzyloxy)benzoic acid

Product 1

HCID 37664104-Benzyloxybenzoylchloride

Procedure

4-Carboxyphenoxy phenyl methane (20g) was converted to the acid chloride by heating under reflux with thionyl chloride for 1hr. Excess thionyl chloride was removed by distillation to yield 4-chlorocarbonylphenoxy phenyl methane.

Workup

  1. temperatureby heating
  2. customExcess thionyl chloride was removed by distillation

Sources & evidence

ORD record
ord-0fdab01ee6eb4d6da66ec148a21483be
Source dataset
uspto-grants-1976_09
Patent number
US03983164

Reaction notes

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