反应详情

A solution of 145 g. of 4-phenyl-1-bromobutane and 179 g. of triphenylphosphine in 350 ml. of toluene is heated at reflux under nitrogen for 16 hours. The mixture is then cooled slowly and ether is added giving a precipitate of (4-phenylbutyl)triphenylphosphonium bromide which is washed thoroughly with benzene/ether and dried 18 hours at 50° C. under reduced pressure, 268 g., m.p. 139°-140° C.

1. temperatureat reflux under nitrogen for 16 hours
2. temperatureThe mixture is then cooled slowly