反应详情

To a solution of 100 g. of 6,9,10-trimethyl-undeca-5,9-dien-2-one in 2,000 ml. of methylene chloride, there was added, while cooling with ice, 100 g. of m-chloro perbenzoic acid. The resulting mixture was allowed to stand while constantly stirring at room temperature for 1 hour. The resulting mixture was diluted with 1,000 ml. of methylene chloride. The resulting solution was washed with ice-cold 1-N sodium hydroxide solution and with a saturated sodium chloride solution, dried over sodium sulfate and evaporated. The residue was fractionally distilled under high vacuum. There was obtained 9,10-epoxy-6,9,10-trimethyl-undec-5-en-2-one. B.p. 89°-91°C./0.07 mm Hg; nD20 = 1.4656.

1. temperaturewhile cooling with ice, 100 g
2. additionThe resulting mixture was diluted with 1,000 ml
3. washThe resulting solution was washed with ice-cold 1-N sodium hydroxide solution and with a saturated sodium chloride solution
4. dry with materialdried over sodium sulfate
5. customevaporated
6. distillationThe residue was fractionally distilled under high vacuum