Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)- → (4-Hydroxyphenyl)(2-phenyl-1-benzofuran-3-yl)methanone

HRID 1577013Notes

Reaction equation

HRID 1577013 reaction equation
C[O:2][C:3]1[CH:25]=[CH:24][C:6]([C:7]([C:9]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[O:11][C:10]=2[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[O:8])=[CH:5][CH:4]=1.Cl.N1C=CC=CC=1>>[OH:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([C:9]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[O:11][C:10]=2[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[O:8])=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 6613416Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)-HCID 10176127Pyridinium chloride

Product 1

HCID 13264991(4-Hydroxyphenyl)(2-phenyl-1-benzofuran-3-yl)methanone

Procedure

3-(4-Methoxybenzoyl)-2-phenylbenzofuran (16.4 g., 0.05 mol.) is combined with 50 g. of freshly distilled pyridine hydrochloride and the mixture is refluxed one hour. The hot mixture is poured with stirring onto an ice-dilute hyrochloric acid mixture and the precipitate is collected to give 3-(4-hydroxybenzoyl)-2-phenylbenzofuran.

Workup

  1. additionThe hot mixture is poured
  2. customthe precipitate is collected

Sources & evidence

ORD record
ord-607c6ff9f85d4943819cdb3b607af565
Source dataset
uspto-grants-1976_09
Patent number
US03983245

Reaction notes

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