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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1577013Generated: November 2, 2026

Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)- → (4-Hydroxyphenyl)(2-phenyl-1-benzofuran-3-yl)methanone

https://huagongshe.com/reaction/1577013

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)-HCID 6613416—
ReactantPyridinium chlorideHCID 10176127—
Product(4-Hydroxyphenyl)(2-phenyl-1-benzofuran-3-yl)methanoneHCID 13264991—

Reaction Steps

3-(4-Methoxybenzoyl)-2-phenylbenzofuran (16.4 g., 0.05 mol.) is combined with 50 g. of freshly distilled pyridine hydrochloride and the mixture is refluxed one hour. The hot mixture is poured with stirring onto an ice-dilute hyrochloric acid mixture and the precipitate is collected to give 3-(4-hydroxybenzoyl)-2-phenylbenzofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03983245
Source datasetuspto-grants-1976_09
ORD IDord-607c6ff9f85d4943819cdb3b607af565
Source noteuspto-grants-1976_09