Thionyl Chloride → HCID 20530897, compound

HRID 1577055Notes

Reaction equation

HRID 1577055 reaction equation
S(Cl)([Cl:3])=O.[Br:5][C:6]1[CH:7]=[C:8]([CH:12]=[CH:13][C:14]=1[O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[C:9](O)=[O:10]>>[Br:5][C:6]1[CH:7]=[C:8]([CH:12]=[CH:13][C:14]=1[O:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[C:9]([Cl:3])=[O:10]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 19884404HCID 19884404, compound

Product 1

HCID 20530897HCID 20530897, compoundYield 97.1%

Procedure

11 g of thionyl chloride was added to 14.5 g (0.046 mol) of the 3-bromo-4-n-heptyloxybenzoic acid prepared in Step II and was gently refluxed for two hours. Excess thionyl chloride was removed by distillation or vacuum distillation to yield 14.9 g of 3-bromo-4-n-heptyloxybenzoyl chloride. The yield was calculated to be 96.8%.

Workup

  1. temperaturewas gently refluxed for two hours
  2. customExcess thionyl chloride was removed by distillation or vacuum distillation

Sources & evidence

ORD record
ord-423209115d8e4b80806c148bbf759eaf
Source dataset
uspto-grants-1981_09
Patent number
US04287085

Reaction notes

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