1-Methylthio-1-methylamino-2-nitroethylene → HCID 131712379, compound

HRID 1577512Notes

Reaction equation

HRID 1577512 reaction equation
[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[O:10][C:9]([CH2:11][NH:12][CH3:13])=[C:8]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:7]=1.[CH3:20][NH:21][C:22](SC)=[CH:23][N+:24]([O-:26])=[O:25]>O>[OH2:10].[CH3:20][NH:21][C:22]([NH:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[O:10][C:9]([CH2:11][NH:12][CH3:13])=[C:8]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:7]=1)=[CH:23][N+:24]([O-:26])=[O:25].[CH3:20][NH:21][C:22]([NH:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[O:10][C:9]([CH2:11][NH:12][CH3:13])=[C:8]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:7]=1)=[CH:23][N+:24]([O-:26])=[O:25]

Participants

4

Reactant 2

HCID 1235491-Methylthio-1-methylamino-2-nitroethyleneHCID 20570927HCID 20570927, compound

Product 1

HCID 131712379HCID 131712379, compoundYield 71.7%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 5-[[2-(amino)ethyl]thio]methyl-N-methyl-3-phenyl-2-furanmethanamine (0.45 g) and N-methyl-1-(methylthio)-2-nitroethenamine (0.24 g) was stirred in water (5 ml) for 24 hours. The solvent was removed in vacuo and the residue purified by column chromatography (Silica/methanol) affording the title compound (0.3 g) as an amber glass.

Workup

  1. customThe solvent was removed in vacuo
  2. customthe residue purified by column chromatography (Silica/methanol)

Sources & evidence

ORD record
ord-7f94373ec7174466ae4671f59ef3195b
Source dataset
uspto-grants-1981_09
Patent number
US04288443

Reaction notes

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