Ammonia → HCID 178510731, compound

HRID 1577534Notes

Reaction equation

HRID 1577534 reaction equation
[Cl:1][C:2]1[CH:20]=[CH:19][CH:18]=[CH:17][C:3]=1[C:4]([C:6]1[S:10][C:9]2[CH:11]=[CH:12][C:13]([Cl:15])=[CH:14][C:8]=2[C:7]=1[OH:16])=O.P(Cl)(Cl)(Cl)(Cl)Cl.[NH3:27]>C(OCC)(=O)C>[NH2:27]/[C:4](/[C:3]1[CH:17]=[CH:18][CH:19]=[CH:20][C:2]=1[Cl:1])=[C:6]1\[C:7](=[O:16])[C:8]2[CH:14]=[C:13]([Cl:15])[CH:12]=[CH:11][C:9]=2[S:10]\1

Participants

5

Reactant 3

HCID 222AmmoniaHCID 24819Phosphorus pentachlorideHCID 20570745HCID 20570745, compound

Product 1

HCID 178510731HCID 178510731, compoundYield 40%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Prepared as in Example 1 from 2-(2-chlorobenzoyl)-5-chlorobenzo[b]thiophen-3-ol, phosphorus(V) chloride and concentrated aqueous ammonia with a yield of 40% of theory; m.p. 199°-201° C. (ethyl acetate).

Sources & evidence

ORD record
ord-b46f33432bd844a0933f3d18d580a111
Source dataset
uspto-grants-1981_09
Patent number
US04288437

Reaction notes

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