Urea → HCID 178510717, compound

HRID 1577555Notes

Reaction equation

HRID 1577555 reaction equation
[C:1]([C:9]1[S:13][C:12]2[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=2[C:10]=1[OH:18])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:19]C(N)=O>>[NH2:19]/[C:1](/[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[C:9]1\[C:10](=[O:18])[C:11]2[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=2[S:13]\1

Participants

3

Reactant 2

HCID 1176UreaHCID 4712192Methanone, (3-hydroxybenzo[b]thien-2-yl)phenyl-

Product 1

HCID 178510717HCID 178510717, compoundYield 55%

Procedure

Prepared as in Example 41 from 2-benzoyl-benzo[b]thiophen-3-ol, but using urea instead of ammonium acetate, with a yield of 55% of theory; m.p. 121°-122° C. (petroleum ether/ethyl acetate 2:1). The product was identical to that of Example 1, based on its TLC, mixed melting point and IR-spectrum.

Workup

  1. additionmixed

Sources & evidence

ORD record
ord-e211d2c4fe964303b317806cdb27a89a
Source dataset
uspto-grants-1981_09
Patent number
US04288437

Reaction notes

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