N,N'-Dimethylurea → HCID 178483127, compound

HRID 1577558Notes

Reaction equation

HRID 1577558 reaction equation
[C:1]([C:9]1[S:13][C:12]2[CH:14]=[CH:15][CH:16]=[CH:17][C:11]=2[C:10]=1[OH:18])(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:19][NH:20]C(NC)=O>C(OCC)(=O)C>[CH3:19][NH:20]/[C:1](/[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)=[C:9]1\[C:10](=[O:18])[C:11]2[CH:17]=[CH:16][CH:15]=[CH:14][C:12]=2[S:13]\1

Participants

4

Reactant 2

HCID 7293N,N'-DimethylureaHCID 4712192Methanone, (3-hydroxybenzo[b]thien-2-yl)phenyl-

Product 1

HCID 178483127HCID 178483127, compoundYield 66%

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Prepared as in Example 31 from 2-benzoyl-benzo[b]thiophen-3-ol, but using N,N'-dimethylurea in place of ammonium acetate, with a yield of 66% of theory, m.p. 156°-157° C. (ethyl acetate). On the basis of its thin-layer chromatogram, mixed melting point, elemental analysis and IR spectrum, the product was identical to that of Example 2.

Workup

  1. additionOn the basis of its thin-layer chromatogram, mixed

Sources & evidence

ORD record
ord-143478e5b90d4374b0cad7f3d23db77f
Source dataset
uspto-grants-1981_09
Patent number
US04288437

Reaction notes

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