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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1577590Generated: October 30, 2026

Ethyl 2-bromopropionate → Ethyl 2-(2,2,2-trifluoro-1-phenylethoxy)propanoate

https://huagongshe.com/reaction/1577590

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-bromopropionateHCID 79040—
ReactantSodium 2,2,2-trifluoro-1-phenylethanolateHCID 86738004—
ProductEthyl 2-(2,2,2-trifluoro-1-phenylethoxy)propanoateHCID 20571138—

Reaction Steps

Using the same procedure as in Example I, Step B, starting from 10.3 g sodium-2,2,2-trifluoro-1-phenylethanolate and 9.4 g ethyl-2-bromopropionate, 6.2 of the title compound is isolated.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04288453
Source datasetuspto-grants-1981_09
ORD IDord-c852748692e047148c4e0a7674ab6624
Source noteuspto-grants-1981_09