Nadide (JAN/USAN/INN) → Lactate

HRID 1577615Notes

Reaction equation

HRID 1577615 reaction equation
[C:1]([O-:9])(=[O:8])[C@H:2]([CH2:4][C:5]([O-:7])=[O:6])[OH:3].C1C=[N+]([C@@H]2O[C@H](COP(OP(OC[C@H]3O[C@@H](N4C5N=CN=C(N)C=5N=C4)[C@H](O)[C@@H]3O)(O)=O)(O)=O)[C@@H](O)[C@H]2O)C=C(C(N)=O)C=1>P([O-])([O-])([O-])=O>[C:1]([O-:9])(=[O:8])[CH:2]([CH2:4][C:5]([O-:7])=[O:6])[OH:3].[C:1]([O-:9])(=[O:8])[CH:2]([CH3:4])[OH:3]

Participants

5

Reactant 2

HCID 5893Nadide (JAN/USAN/INN)HCID 5459792HCID 5459792, compound

Product 2

HCID 91435LactateHCID 160434DL-Malate

Reagents, catalysts & solvents 1

HCID 1061PhosphateSolvent

Procedure

4 g dry weight of cells immobilized as described in Example 17 were added to 50 ml 25 mM L-malate in 0.1 M phosphate of pH 5.0 together with 85 μmol NAD+ and 35 μmol MnCl2. Total conversion of malate to lactate was obtained in 3 hrs. The procedure could be repeated at least five times without any increase in reaction time.

Workup

  1. custom4 g dry weight of cells immobilized

Sources & evidence

ORD record
ord-e2386fd5b9504ea59d6f445405e5d560
Source dataset
uspto-grants-1981_09
Patent number
US04288552

Reaction notes

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