Hydrogen Bromide → HCID 20569238, compound

HRID 1577753Notes

Reaction equation

HRID 1577753 reaction equation
C[O:2][C:3]1[CH:8]=[C:7]([CH3:9])[C:6]([O:10]C)=[CH:5][C:4]=1[CH2:12][CH2:13][C:14]([OH:16])=[O:15].Br>>[OH:2][C:3]1[CH:8]=[C:7]([CH3:9])[C:6]([OH:10])=[CH:5][C:4]=1[CH2:12][CH2:13][C:14]([OH:16])=[O:15]

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 205692362,5-Dimethoxy-4-methylbenzenepropanoic acid

Product 1

HCID 20569238HCID 20569238, compound

Procedure

0.18 mol (40 g) of 3-(2',5'-dimethoxy-4'-methylphenyl)-propionic acid is heated under reflux in 300 ml of 48% strength hydrobromic acid. After cooling, the acid obtained precipitates. It is filtered off, dried and recrystallised from a mixture of ethanol, chloroform and petroleum ether. After drying, it melts at 181° C.

Workup

  1. temperatureAfter cooling
  2. customthe acid obtained
  3. customprecipitates
  4. filtrationIt is filtered off
  5. customdried
  6. customrecrystallised from a mixture of ethanol, chloroform and petroleum ether
  7. customAfter drying

Sources & evidence

ORD record
ord-e3ddedbec2cb466ead28bee6584b382f
Source dataset
uspto-grants-1981_09
Patent number
US04289495

Reaction notes

Loading…