反应详情

An acetic acid (50 ml.) solution of ω-thiocaprolactam (6.5 g., 0.05 mole) and α-bromophenylacetic acid (10.8 g., 0.05 mole) was heated on a steam bath for 1/2 hour. The solution was first cooled and diluted with ether. Upon scratching solid which precipitated was collected. The crude material was recrystallized from acetonitrile. The purified material weighed 14 g. (86% yield) and melted at 172°-175° C.

1. temperatureThe solution was first cooled
2. customprecipitated
3. customwas collected
4. customThe crude material was recrystallized from acetonitrile