HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 20569974, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | HCID 20569954 | HCID 20569954 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 20569974 | HCID 20569974 | — |
Reaction Steps
18 g of bromine is added dropwise, with stirring, to a solution of 28.2 g of 5-methyl-6-(4'-fluoro-4-biphenyl-yl)-2,3,4,5-tetrahydropyridazin-3-one in 500 ml of acetic acid at 100°; the mixture is then heated for an additional 15 minutes at 100°, cooled and filtered. 5-Methyl-6-(4'-fluoro-4-biphenylyl)-2,3-dihydropyridazin-3-one is obtained. m.p. 245°-247°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04289774 |
| Source dataset | uspto-grants-1981_09 |
| ORD ID | ord-9a8e6d7ac2fd4392bf2c74149eb2e53e |
| Source note | uspto-grants-1981_09 |