3-Bromophenyl isothiocyanate → N-(3-bromophenyl)-2-decyltetrahydro-2H-1,3-thiazine3-carbothioamide

HRID 1577817Notes

Reaction equation

HRID 1577817 reaction equation
[CH2:1]([CH:11]1[NH:16][CH2:15][CH2:14][CH2:13][S:12]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10].[Br:17][C:18]1[CH:19]=[C:20]([N:24]=[C:25]=[S:26])[CH:21]=[CH:22][CH:23]=1>>[Br:17][C:18]1[CH:19]=[C:20]([NH:24][C:25]([N:16]2[CH2:15][CH2:14][CH2:13][S:12][CH:11]2[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH3:10])=[S:26])[CH:21]=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 164813-Bromophenyl isothiocyanateHCID 205696232-decyltetrahydro-2H-1,3-thiazine

Product 1

HCID 12783515N-(3-bromophenyl)-2-decyltetrahydro-2H-1,3-thiazine3-carbothioamide

Procedure

The procedure of Example 25 was repeated, except that the reactants consisted of 0.9 g. of 2-decyltetrahydro-2H-1,3-thiazine and 0.7 g. of 3-bromophenyl isothiocyanate. The product was recrystallized from ethanol to give N-(3-bromophenyl)-2-decyltetrahydro-2H-1,3-thiazine3-carbothioamide, m.p. 73°-4°. The following elemental microanalysis was obtained:

Workup

  1. customThe product was recrystallized from ethanol

Sources & evidence

ORD record
ord-31baf5a016914eddb43065a33786e0d9
Source dataset
uspto-grants-1981_09
Patent number
US04289766

Reaction notes

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