HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Pyridinebutanamide → 4-(Piperidin-4-yl)butanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Pyridinebutanamide | HCID 12136640 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-(Piperidin-4-yl)butanamide | HCID 21949235 | — |
Reaction Steps
The crude amide was dissolved in glacial acetic acid and hydrogenated at 60°/60 p.s.i. over a platinum oxide catalyst until uptake of hydrogen ceased. The catalyst was removed by filtration and the filtrate was evaporated in vacuo to give crude 4-(piperid-4-yl)butyramide as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04289772 |
| Source dataset | uspto-grants-1981_09 |
| ORD ID | ord-84b1bf2f9a3a48a78a60fdfdc7b7000f |
| Source note | uspto-grants-1981_09 |