Water → HCID 20570078, compound

HRID 1577855Notes

Reaction equation

HRID 1577855 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([OH:10])[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].[CH2:11]([CH:13]1[O:15][CH2:14]1)Cl.[OH-:16].[K+].[OH2:18]>C(O)(C)C>[N+:1]([C:4]1[CH:5]=[C:6]([CH:7]=[CH:8][CH:9]=1)[O:10][CH2:7][CH:6]([OH:10])[CH2:14][O:15][C:13]1[CH:11]=[CH:8][CH:9]=[C:4]([N+:1]([O-:18])=[O:16])[CH:5]=1)([O-:3])=[O:2]

Participants

6

Reactant 4

HCID 962WaterHCID 7835EpichlorohydrinHCID 111373-NitrophenolHCID 14797Potassium Hydroxide

Product 1

HCID 20570078HCID 20570078, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent2×

Procedure

44.3 g. (0.32 mole) of 3-nitrophenol is dissolved in 1.2 liter of isopropanol; 13.7 ml. of epichlorohydrin is added thereto and then a solution of 17.5 g. of potassium hydroxide in 250 ml. of isopropanol as well as 10 ml. of water are introduced. The mixture is refluxed for 48 hours, concentrated to half its volume, and combined with 250 ml. of water. The thus-precipitated product is filtered off, washed with water, and dried.

Workup

  1. temperatureThe mixture is refluxed for 48 hours
  2. concentrationconcentrated to half its volume
  3. filtrationThe thus-precipitated product is filtered off
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-dc95abf073694494af9e013ac66f8553
Source dataset
uspto-grants-1981_09
Patent number
US04289777

Reaction notes

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