Hydrochloric Acid → HCID 70521993, compound

Participants

Reaction Steps

7.6 Grams of 1-methyl-4-(4-chlorophenyl)butylamine was reacted with 9.9 ml. of ninety percent formic acid and 9.5 ml. of thirty-seven percent aqueous formaldehyde to provide 7.05 g. of N,N-dimethyl-1-methyl-4-(4-chlorophenyl)butylamine. The free amine was reacted with hydrogen chloride to form N,N-dimethyl-1-methyl-4-(4-chlorophenyl)butylaminium chloride. M.P. 109°-111° C.

Provenance & Evidence