Hydrochloric Acid → HCID 70521993, compound

HRID 1577890Notes

Reaction equation

[CH3:1][N:2]([CH:4]([CH3:15])[CH2:5][CH2:6][CH2:7][C:8]1[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][CH:9]=1)[CH3:3].Cl>>[Cl-:14].[CH3:1][NH+:2]([CH:4]([CH3:15])[CH2:5][CH2:6][CH2:7][C:8]1[CH:9]=[CH:10][C:11]([Cl:14])=[CH:12][CH:13]=1)[CH3:3]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 12951638HCID 12951638, compound

Product 1

HCID 70521993HCID 70521993, compound

Procedure

7.6 Grams of 1-methyl-4-(4-chlorophenyl)butylamine was reacted with 9.9 ml. of ninety percent formic acid and 9.5 ml. of thirty-seven percent aqueous formaldehyde to provide 7.05 g. of N,N-dimethyl-1-methyl-4-(4-chlorophenyl)butylamine. The free amine was reacted with hydrogen chloride to form N,N-dimethyl-1-methyl-4-(4-chlorophenyl)butylaminium chloride. M.P. 109°-111° C.

Sources & evidence

ORD record: ord-654255534edd4e4087aa52be06578185
Source dataset: uspto-grants-1981_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04289787

Reaction notes

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