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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1577918Generated: November 4, 2026

Picolyl chloride hydrochloride → N-Cyano-N'-(2-propyn-1-yl)-N"-{2-[(2-pyridyl)methylthio]ethyl}guanidine

https://huagongshe.com/reaction/1577918

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPicolyl chloride hydrochlorideHCID 23392—
ReactantN-Cyano-N'-propargyl-N"-(2-mercaptoethyl)guanidineHCID 136182246—
ProductN-Cyano-N'-(2-propyn-1-yl)-N"-{2-[(2-pyridyl)methylthio]ethyl}guanidineHCID 136023173—

Reaction Steps

The ethanolic solution of the product of Step A is reacted with about an equimolar amount of 2-chloromethylpyridine hydrochloride and about two equivalents of base to produce the title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04289876
Source datasetuspto-grants-1981_09
ORD IDord-9acfcd3a79d04c1a9faba53d6cdc1905
Source noteuspto-grants-1981_09