Ethanol → HCID 53656875, compound

Participants

Reaction Steps

11.15 g (0.1 mole) semicarbazide hydrochloride are dissolved in 10 ml water in a three neck 100 ml round flask with stirrer and thermometer and 10.0 g (0.1 mole) potassium hydrogen carbonate are added and then 10 ml ethanol are employed to thin. To this during 5 minutes are added drop by drop 9.8 g (0.1 mole) propiolic acid ethyl ester. The reaction temperature is kept for 4 hours at about 30° C. and a thick crystal paste forms slowly. After standing over night the product is cooled down in an ice bath and thinned with 10 ml water. The crystals are sucked off, are washed with 10 ml water and dried in vacuo at 40° C. to constant weight.

Provenance & Evidence