HRID1578024

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：c1ccc(-c2ccccc2)cc1.c1ccc(Oc2ccccc2)cc1

HCID24670

Phenyl ether-biphenyl mixture

C24H20O

结构：CC(=O)OCC(=O)[C@@]1(OC(C)=O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

HCID102165

17,21-Bis(acetyloxy)pregn-4-ene-3,20-dione

C25H34O6

PRODUCTS

生成物

结构：CC(=O)OCC(=O)C1=CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C

HCID15674000

未命名化合物

收率 83%

PROCEDURE

实验过程

One gram of 17α,21-diacetoxy-4-pregnene-3,20-dione is heated analogously to Example 1 in "Dowtherm" for 80 minutes to 285° C., worked up, separated, and combined. Recrystallization from hexane/ethyl acetate yields 700 mg of 21-acetoxy-4,16-pregnadiene-3,20-dione (83% of theory), m.p. 146°-148° C.

WORKUP

后处理

customseparated
customRecrystallization from hexane/ethyl acetate