HRID1578025

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：c1ccc(-c2ccccc2)cc1.c1ccc(Oc2ccccc2)cc1

HCID24670

Phenyl ether-biphenyl mixture

C24H20O

结构：CC(=O)OCC(=O)[C@@]1(OC(C)=O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

HCID14233395

Pregna-1,4-diene-3,20-dione, 17,21-bis(acetyloxy)-11-hydroxy-, (11beta)-

C25H32O7

PRODUCTS

生成物

结构：CC(=O)OCC(=O)C1=CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]12C

HCID102365

11-Hydroxy-3,20-dioxopregna-1,4,16-trien-21-yl acetate

C23H28O5

收率 81%

PROCEDURE

实验过程

One gram of 17α,21-diacetoxy-11β-hydroxy-1,4- pregnadiene-3,20-dione is treated analogously to Example 1 in "Dowtherm" for 50 minutes at 250° C. and worked up. Recrystallization from isopropyl ether yields 700 mg of 21-acetoxy-11β-hydroxy-1,4,16-pregnatriene-3,20-dione (81% of theory).

WORKUP

后处理

customRecrystallization from isopropyl ether