Butyl bromide → HCID 178454975, compound

Participants

Reaction Steps

5.2 g (0.02 M) of N-(2,6-dichlorophenyl)-N'-acetyl-thiourea, 2.1 ml (0.015 M) of ground potassium carbonate, 3.2 ml (0.03 M) of n-butylbromide and 50 ml of acetone are boiled in a reflux under energetic shaking for 4 hours. The acetone is distilled off. The residue in the flask is washed with water and filtered. 5.8 g (90.6% of the theoretical yield) of N-(2,6-dichlorophenyl)-N'-acetyl-S-n-butylisothiourea with a melting point of 84°-89° are obtained. After recrystallization from ethanol the product has a melting point of 97°-100°.

Provenance & Evidence