Hydrochloric Acid → HCID 18928137, compound

HRID 1578077Notes

Reaction equation

HRID 1578077 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[Br:12])[N:8]1[CH:13]=[C:14]([C:16]([O:18]CC)=[O:17])[N:15]=[C:7]1[C:6]([O:21]CC)=[N:5]2.C(O)C.[OH-].[Na+].Cl>O>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[Br:12])[N:8]1[CH:13]=[C:14]([C:16]([OH:18])=[O:17])[N:15]=[C:7]1[C:6](=[O:21])[NH:5]2

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 14798Sodium HydroxideHCID 20568840HCID 20568840, compound

Product 1

HCID 18928137HCID 18928137, compoundYield 60.7%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A suspension of 0.1 g of the product of Step C, 10 ml of ethanol, 20 ml of water and 3 ml of 1 N sodium hydroxide solution was refluxed overnight and the resulting clear solution was acidified with concentrated hydrochloric acid. The mixture was filtered to obtain 0.053 g of 4,5-dihydro-7,8-dibromo-4-oxoimidazo-[1,2-a]-quinoxaline-2-carboxylic acid as a buff crystalline solid.

Workup

  1. temperaturewas refluxed overnight
  2. filtrationThe mixture was filtered

Sources & evidence

ORD record
ord-adc7df2a5b0f4608ad2b003f945e0424
Source dataset
uspto-grants-1981_09
Patent number
US04291033

Reaction notes

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