反应详情

温度

105 °C

27 g of 24-oxocholesterol was dissolved in 717 ml of anhydrous benzene. To the solution were added 179 ml of ethylene glycol and 358 mg of p-toluen sulfonic acid. The mixture was stirred and heated at a bath temperature of 105° C. for 20 hours in a flask equipped with receiver capable of mesuring water in which was added a molecular sieve. Water was added to separate the reaction mixture into layers. The aqueous layer was extracted with benzene.

1. additionwas added a molecular sieve
2. customto separate the reaction mixture into layers
3. extractionThe aqueous layer was extracted with benzene