4-Phenylpiperidine → HCID 21559972, compound

HRID 1578411Notes

Reaction equation

[C:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([O:13][CH3:14])=[CH:10][CH:11]=2)[CH:6]([CH2:15][CH2:16]Br)[CH:5]1[CH3:18])(=[O:3])[CH3:2].[C:19]1([CH:25]2[CH2:30][CH2:29][NH:28][CH2:27][CH2:26]2)[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[C:1]([N:4]1[C:12]2[C:7](=[CH:8][C:9]([O:13][CH3:14])=[CH:10][CH:11]=2)[CH:6]([CH2:15][CH2:16][N:28]2[CH2:29][CH2:30][CH:25]([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[CH2:26][CH2:27]2)[CH:5]1[CH3:18])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 698734-Phenylpiperidine

HCID 21559964HCID 21559964, compound

Product 1

HCID 21559972HCID 21559972, compound

Procedure

In the manner described in Example 1, treatment of 1-acetyl-3-(2-bromoethyl)-5-methoxy-2-methylindoline with 4-phenylpiperidine gives the product as an amorphous solid.

Sources & evidence

ORD record: ord-83294536779b40cbba805b338d6b1887
Source dataset: uspto-grants-1976_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03936464

Reaction notes

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