Hydrochloric Acid → HCID 21503021, compound

HRID 1578454Notes

Reaction equation

HRID 1578454 reaction equation
[CH:1]([O:4][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[C:7](=[O:15])[CH2:8][C:9]2=[O:14])([CH3:3])[CH3:2].[N+:16]([O-])([OH:18])=[O:17].Cl>CCOCC>[CH:1]([O:4][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[C:7](=[O:15])[CH:8]([N+:16]([O-:18])=[O:17])[C:9]2=[O:14])([CH3:3])[CH3:2]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 944Nitric AcidHCID 21503044HCID 21503044, compound

Product 1

HCID 21503021HCID 21503021, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

4-Isopropyloxy indane-1,3-dione (0.16 g; 0.003 mole) suspended in dry ether (5 ml) was treated dropwise and with stirring with fuming nitric acid (1.0 ml) at 10°C. The resulting dark solution was treated with 5N hydrochloric acid and evaporated to a yellow crystalline product; m.p. (water, hydrochloric acid) 80°-81°C. (Found: C, 57.94; H, 4.43; N, 5.46; C12H11NO5 requires: C, 57.83; H, 4.45; N, 5.62%).

Workup

  1. additionwas treated dropwise
  2. customevaporated to a yellow crystalline product
  3. customm.p. (water, hydrochloric acid) 80°-81°C. (Found: C, 57.94; H, 4.43; N, 5.46; C12H11NO5 requires: C, 57.83; H, 4.45; N, 5.62%)

Sources & evidence

ORD record
ord-f9a9aff9923f4fb0a36be665cba5bffd
Source dataset
uspto-grants-1976_02
Patent number
US03936504

Reaction notes

Loading…