N,O-Dimethylhydroxylamine →

HRID 1578469Notes

Reaction equation

HRID 1578469 reaction equation
[Cl:1]([C:5]1[CH:6]=[C:7]([N:11]=[C:12]=[O:13])[CH:8]=[CH:9][CH:10]=1)(=[O:4])(=[O:3])=[O:2].[CH3:14][O:15][NH:16][CH3:17]>CCOCC.CO>[CH3:14][O:15][N:16]([CH3:17])[C:12]([NH:11][C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([Cl:1](=[O:4])(=[O:3])=[O:2])[CH:6]=1)=[O:13]

Participants

3

Reactant 1

HCID 14232N,O-Dimethylhydroxylamine

Product 0

No Product data yet.

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 3283Diethyl EtherSolvent

Procedure

To a solution of 12.9 grams (0.064 mole) of IV in 250 milliliters of ether was added a solution of 4.9 grams (0.08 mole) of O,N-dimethylhydroxylamine in 350 milliliters of methanol. The resulting mixture was concentrated to dryness, washed with water and recrystallized from acetone/hexane (5:1) to give 11.8 grams (71% yield) of V as a white crystalline solid, melting point: 125°-126°. Its identity was confirmed by elemental analysis.

Workup

  1. concentrationThe resulting mixture was concentrated to dryness
  2. washwashed with water
  3. customrecrystallized from acetone/hexane (5:1)

Sources & evidence

ORD record
ord-90c23fef7f1043a9a4b12fdbf71adf36
Source dataset
uspto-grants-1976_02
Patent number
US03937627

Reaction notes

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