HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → 7-Chloro-1-methyl-3-(methylsulfonyl)-4(1H)-cinnolinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | 1-methyl-3-(methylsulfonyl)cinnolin-4(1H)-one | HCID 12421487 | — |
| Reactant | 7-chloro-1-methyl-3-(methylsulfinyl)-4(1H)-cinnolinone | HCID 21559126 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 7-Chloro-1-methyl-3-(methylsulfonyl)-4(1H)-cinnolinone | HCID 21559129 | — |
Reaction Steps
This was prepared by oxidizing a solution of 10 g of 7-chloro-1-methyl-3-(methylsulfinyl)-4(1H)-cinnolinone in 500 ml of CHCl3 with 7.5 g of m-chloroperbenzoic acid in analogous fashion to 1-methyl-3-(methylsulfonyl)-4(1H)-cinnolinone. The material was recrystallized from CH3CN, m.p. 270°-72°; yield 7.5 g (71%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03937704 |
| Source dataset | uspto-grants-1976_02 |
| ORD ID | ord-67ff0b3de7a543ed9f74d3ddf356c350 |
| Source note | uspto-grants-1976_02 |