Triethylamine → HCID 68137482, compound

HRID 1578711Notes

Reaction equation

HRID 1578711 reaction equation
[CH3:1][C:2]1([CH3:24])[S:6][C@@H:5]2[C@H:7]([NH:10][C:11]([C@H:13]([NH2:20])[C:14]3[CH2:19][CH:18]=[CH:17][CH2:16][CH:15]=3)=[O:12])[C:8](=[O:9])[N:4]2[C@H:3]1[C:21]([OH:23])=[O:22].S([O-])([O-])(=O)=O.[Mg+2].[CH2:31]([N:33]([CH2:36][CH3:37])[CH2:34][CH3:35])[CH3:32].CN(C)P(N(C)C)(N(C)C)=O>ClCCl>[CH3:1][C:2]1([CH3:24])[S:6][C@@H:5]2[C@H:7]([NH:10][C:11]([C@H:13]([NH2:20])[C:14]3[CH2:19][CH:18]=[CH:17][CH2:16][CH:15]=3)=[O:12])[C:8](=[O:9])[N:4]2[C@H:3]1[C:21]([OH:23])=[O:22].[CH2:31]([N:33]([CH2:36][CH3:37])[CH2:34][CH3:35])[CH3:32]

Participants

6

Reactant 4

HCID 8471TriethylamineHCID 12679HexamethylphosphoramideHCID 24083Sulfuric acid magnesium salt (1:1)HCID 71392Epicillin

Product 1

HCID 68137482HCID 68137482, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of 1 g. of epicillin, 0.5 g. of anhydrous magnesium sulfate, 0.7 ml. of triethylamine, 5 ml. of hexamethylphosphoramide, and 25 ml. of dichloromethane was stirred for 30 minutes at room temperature and then magnesium sulfate was filtered off to provide a dichloromethane solution of epicillin triethylamine salt.

Workup

  1. additionA mixture of 1 g
  2. filtrationmagnesium sulfate was filtered off

Sources & evidence

ORD record
ord-d96926aad57644d79fde8fff75380d61
Source dataset
uspto-grants-1976_02
Patent number
US03939150

Reaction notes

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