Hydrochloric Acid → HCID 21558602, compound

Participants

Reaction Steps

A reaction identical with that of Example 3 is performed on the 3-methylsulfinylacetyl-5-phenylisoxazole (1.25 g) prepared in a manner similar to that described in Example 1 or 2 with the exception that the ethyl acetate solution of hydrogen chloride is replaced by a solution of acetyl bromide (741 mg, 6.025 milimoles) in dichloromethane (10 ml) to give 3-(2-methylthio-2-bromoacetyl)-5-phenylisoxazole (1.62 g, 103.5 %) as a crude crystalline residue.

Provenance & Evidence