2-Methylcyclohexylamine → 4-(2-Methylcyclohexylamino)-7-nitro-2,5-bis(trifluoromethyl)-benzimidazole

HRID 1578724Notes

Reaction equation

HRID 1578724 reaction equation
Cl[C:2]1[C:10]2[NH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[N:7][C:6]=2[C:5]([N+:15]([O-:17])=[O:16])=[CH:4][C:3]=1[C:18]([F:21])([F:20])[F:19].[CH3:22][CH:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH:24]1[NH2:29]>>[CH3:22][CH:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH:24]1[NH:29][C:2]1[C:10]2[NH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[N:7][C:6]=2[C:5]([N+:15]([O-:17])=[O:16])=[CH:4][C:3]=1[C:18]([F:21])([F:20])[F:19]

Participants

3

Reactant 2

HCID 234322-MethylcyclohexylamineHCID 1355549354-Chloro-7-nitro-2,5-bis(trifluoromethyl)benzimidazole

Product 1

HCID 1357839434-(2-Methylcyclohexylamino)-7-nitro-2,5-bis(trifluoromethyl)-benzimidazole

Procedure

4-Chloro-7-nitro-2,5-bis(trifluoromethyl)benzimidazole is reacted with 2-methylcyclohexylamine to obtain 4-(2-methylcyclohexylamino)-7-nitro-2,5-bis(trifluoromethyl)-benzimidazole, which is reacted with potassium ethoxide to yield the corresponding potassium salt, m.w., 448.4.

Sources & evidence

ORD record
ord-9d1993fb42884a8c9c12fedd5e52cd66
Source dataset
uspto-grants-1976_02
Patent number
US03939166

Reaction notes

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