Cyclopentaneethanol → 4-(2-Cyclopentylethoxy)-7-nitro-2,5-bis(trifluoromethyl)benzimidazole

HRID 1578730Notes

Reaction equation

HRID 1578730 reaction equation
Cl[C:2]1[C:10]2[NH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[N:7][C:6]=2[C:5]([N+:15]([O-:17])=[O:16])=[CH:4][C:3]=1[C:18]([F:21])([F:20])[F:19].[Na].[CH:23]1([CH2:28][CH2:29][OH:30])[CH2:27][CH2:26][CH2:25][CH2:24]1>>[CH:23]1([CH2:28][CH2:29][O:30][C:2]2[C:10]3[NH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[N:7][C:6]=3[C:5]([N+:15]([O-:17])=[O:16])=[CH:4][C:3]=2[C:18]([F:21])([F:20])[F:19])[CH2:27][CH2:26][CH2:25][CH2:24]1

Participants

4

Reactant 3

HCID 69833CyclopentaneethanolHCID 5360545SodiumHCID 1355549354-Chloro-7-nitro-2,5-bis(trifluoromethyl)benzimidazole

Product 1

HCID 537520804-(2-Cyclopentylethoxy)-7-nitro-2,5-bis(trifluoromethyl)benzimidazole

Procedure

4-Chloro-7-nitro-2,5-bis(trifluoromethyl)benzimidazole is reacted with the sodium salt of 2-cyclopentylethanol to obtain 4-(2-cyclopentylethoxy) -7-nitro-2,5-bis(trifluoromethyl)benzimidazole, m.w., 397.3.

Sources & evidence

ORD record
ord-fc98851d82c6465e99b431806d4061ca
Source dataset
uspto-grants-1976_02
Patent number
US03939166

Reaction notes

Loading…