Piperidine → HCID 21558573, compound

HRID 1578732Notes

Reaction equation

Cl[C:2]1[C:10]2[NH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[N:7][C:6]=2[C:5]([N+:15]([O-:17])=[O:16])=[CH:4][C:3]=1[C:18]#[N:19].[NH:20]1[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1>>[N:20]1([C:2]2[C:10]3[NH:9][C:8]([C:11]([F:14])([F:13])[F:12])=[N:7][C:6]=3[C:5]([N+:15]([O-:17])=[O:16])=[CH:4][C:3]=2[C:18]#[N:19])[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21]1

Participants

Reactant 2

HCID 8082Piperidine

HCID 135783926HCID 135783926, compound

Product 1

HCID 21558573HCID 21558573, compound

Procedure

4-Chloro-7-nitro-5-cyano-2-trifluoromethylbenzimidazole is reacted with piperidine to obtain 4-piperidino-7-nitro-5-cyano-2-trifluoromethylbenzimidazole, m.w., 339.3. This compound is reacted with calcium oxide to obtain the corresponding calcium salt, m.w., 716.6.

Sources & evidence

ORD record: ord-395be11dca9e4cf2aaebaa8ba800ed30
Source dataset: uspto-grants-1976_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03939166

Reaction notes

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