反应详情

The method of preparing 4-aminothiazole comprising reacting 2-bromo-4-trifluoroacetamidothiazole under low pressure catalytic hydrogenation conditions in the presence of a noble metal catalyst to give 4-trifluoroacetamidothiazole then reacting said 4-trifluoroacetamidothiazole with sodium or potassium hydroxide in an aqueous medium at from about 30°-35°C. for about 4-8 hours.