Hydrochloric Acid → HCID 21557329, compound

HRID 1578929Notes

Reaction equation

HRID 1578929 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([CH:8]([CH3:10])[OH:9])[C:5]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][CH:12]=2)=[C:4]([NH2:18])[N:3]=1.Cl>CCOCC>[ClH:17].[NH2:1][C:2]1[N:7]=[C:6]([CH:8]([CH3:10])[OH:9])[C:5]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][CH:12]=2)=[C:4]([NH2:18])[N:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 3239151-[2,6-diamino-5-(4-chlorophenyl)pyrimidin-4-yl]ethanol

Product 1

HCID 21557329HCID 21557329, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent2×

Procedure

Dissolving (±)-2,6-diamino-5-(p-chlorophenyl)-α-methyl-4-pyrimidine methanol in a sufficient amount of ether and adding an ether solution saturated with HCl gas, gave (±)-2,6-diamino-5-(p-chlorophenyl)-α-methyl-4-pyrimidine methanol, hydrochloride, m.p. 265°-269°.

Sources & evidence

ORD record
ord-21b46dd14e3041db99c8ebdefe6ac04f
Source dataset
uspto-grants-1976_02
Patent number
US03940393

Reaction notes

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