Ethanol → HCID 86733080, compound

HRID 1578945Notes

Reaction equation

HRID 1578945 reaction equation
C([O:3][C:4](=O)[CH2:5][S:6][C:7]1[N:12]=[C:11]([Cl:13])[CH:10]=[C:9]([NH:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([CH3:21])[C:16]=2[CH3:22])[N:8]=1)C.O.[NH2:25][NH2:26].C(O)C>O>[Cl:13][C:11]1[CH:10]=[C:9]([NH:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([CH3:21])[C:16]=2[CH3:22])[N:8]=[C:7]([S:6][CH2:5][C:4]([NH:25][NH2:26])=[O:3])[N:12]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 24654Hydrazine hydrate (1:1)HCID 9798569HCID 9798569, compound

Product 1

HCID 86733080HCID 86733080, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 5.0 g of [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid ethyl ester and 5.0 g of hydrazine hydrate (98%) in 40 ml. of ethanol was allowed to stand overnight at room temperature. Water was added to the mixture until a precipitate appeared. This material was recrystallized from ethanol affording 4.8 g of product, mp. 185°-189°C.

Workup

  1. customThis material was recrystallized from ethanol affording 4.8 g of product, mp. 185°-189°C.

Sources & evidence

ORD record
ord-57d00965638a469a975d14271d94bcd2
Source dataset
uspto-grants-1976_02
Patent number
US03940394

Reaction notes

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