1,4-Dibromobutane → 2-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dione

HRID 1579010Notes

Reaction equation

HRID 1579010 reaction equation
Cl.N1C=CC=CC=1N1CCN([CH2:14][CH2:15][CH2:16][CH2:17][N:18]2[C:27](=[O:28])[C:26]3[CH:29]=[CH:30][CH:31]=[C:24]4[C:25]=3[C:20](=[CH:21][CH:22]=[CH:23]4)[C:19]2=[O:32])CC1.[Br:33][CH2:34]CCCCBr.BrCCCCBr>>[Br:33][CH2:34][CH2:14][CH2:15][CH2:16][CH2:17][N:18]1[C:27](=[O:28])[C:26]2[CH:29]=[CH:30][CH:31]=[C:24]3[C:25]=2[C:20](=[CH:21][CH:22]=[CH:23]3)[C:19]1=[O:32]

Participants

4

Reactant 3

HCID 80561,4-DibromobutaneHCID 81001,5-DibromopentaneHCID 1317100602-[4-[4-(2-Pyridinyl)-1-piperazinyl]butyl]-1H-benz[de]-isoquinoline-1,3-(2H)-dione, hydrochloride

Product 1

HCID 166387912-(5-Bromopentyl)benzo[de]isoquinoline-1,3-dione

Procedure

Following the procedure of part (a) of example 46 but substituting 1,5-dibromopentane for the 1,4-dibromobutane, one obtains 2-(5-bromopentyl)-1H-benz[de]isoquinoline-1,3(2H)-dione; m.p. 113°-115°.

Sources & evidence

ORD record
ord-f4515deedec74caead3f82680a7d0a0e
Source dataset
uspto-grants-1976_02
Patent number
US03940398

Reaction notes

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