HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-bromobutyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione → 2-[6-[4-(2-pyridinyl)-1-piperazinyl]-hexyl]-1H-benz[de]isoquinoline-1,3(2H)-dione, hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-bromobutyl)-1H-benzo[de]isoquinoline-1,3(2H)-dione | HCID 2782360 | — |
| Reactant | 2-(6-bromohexyl)-1H-benz[de]isoquinoline-1,3(2H)-dione | HCID 20364507 | — |
| Reactant | 2-[4-[4-(2-Pyridinyl)-1-piperazinyl]butyl]-1H-benz[de]-isoquinoline-1,3-(2H)-dione, hydrochloride | HCID 131710060 | — |
| Product | 2-[6-[4-(2-pyridinyl)-1-piperazinyl]-hexyl]-1H-benz[de]isoquinoline-1,3(2H)-dione, hydrochloride | HCID 131710062 | — |
Reaction Steps
Following the procedure of part (b) of example 46 but substituting 2-(6-bromohexyl)-1H-benz[de]isoquinoline-1,3(2H)-dione for the 2-(4-bromobutyl)-1H-benz[de]isoquinoline-1,3-(2H)-dione, one obtains 2-[6-[4-(2-pyridinyl)-1-piperazinyl]-hexyl]-1H-benz[de]isoquinoline-1,3(2H)-dione, hydrochloride (1:2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03940398 |
| Source dataset | uspto-grants-1976_02 |
| ORD ID | ord-8aac111b24354791b43eb39c2a44dd1c |
| Source note | uspto-grants-1976_02 |