Methyl Bromide → HCID 10355438, compound

HRID 1579048Notes

Reaction equation

HRID 1579048 reaction equation
[O:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH:2]1[O:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1CC(O)=O.[O:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH:19]1[O:24][C:25]1[CH:26]=[C:27](CC(O)=O)[CH:28]=[CH:29][CH:30]=1.CBr>>[CH3:4][CH:3]([C:26]1[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=1[O:24][CH:19]1[CH2:20][CH2:21][CH2:22][CH2:23][O:18]1)[C:2]([O:1][CH3:6])=[O:7].[CH3:21][CH:20]([C:12]1[CH:11]=[CH:10][CH:9]=[C:8]([O:7][CH:2]2[CH2:3][CH2:4][CH2:5][CH2:6][O:1]2)[CH:13]=1)[C:19]([O:18][CH3:23])=[O:24]

Participants

5

Reactant 3

HCID 6323Methyl BromideHCID 19428328HCID 19428328, compoundHCID 53927775HCID 53927775, compound

Product 2

HCID 10355438HCID 10355438, compoundHCID 21557718HCID 21557718, compound

Procedure

By the same method but using 2-(tetrahydropyran-2-yloxy) phenylacetic acid and 3-(tetrahydropyran-2-yloxy)-phenylacetic acid in place of 4-(tetrahydropyran-2-yloxy)-phenylacetic acid and methyl bromide as alkylating agent there are obtained methyl 2-methyl-2-(2-tetrahydropyran-2-yloxyphenyl)acetate and methyl 2-methyl-2-(3-tetrahydropyran-2-yloxyphenyl)acetate, respectively.

Sources & evidence

ORD record
ord-081b052b4e5a49188b8566a3fd132d8e
Source dataset
uspto-grants-1976_02
Patent number
US03940407

Reaction notes

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