Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → 4-[4(3-Amino-2-hydroxypropoxy)phenyl]-1,2,3-thiadiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | 4-[4-(Oxiran-2-ylmethoxy)phenyl]-1,2,3-thiadiazole | HCID 2737103 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-[4(3-Amino-2-hydroxypropoxy)phenyl]-1,2,3-thiadiazole | HCID 21557596 | — |
반응 단계
A solution of 200 mg. of 4-[4(2,3-epoxypropoxy) phenyl]-1,2,3-thiadiazole in 10 ml. of anhydrous ethanol is saturated with ammonia and the reaction mixture is maintained at room temperature for 16 hours. The reaction mixture is then evaporated to dryness under vacuo, to yield the crude 4-[4(3-amino-2-hydroxypropoxy)phenyl]-1,2,3-thiadiazole, which can be further purified by thin layer chromatography.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03940407 |
| 출처 데이터셋 | uspto-grants-1976_02 |
| ORD ID | ord-3e6724cf9771496f91d46c0605645b5c |
| 출처 메모 | uspto-grants-1976_02 |