Hydrochloric Acid → HCID 12291086, compound

Participants

Reaction Steps

A mixture of 15 parts of methyl 7-chloro-1-phenyl-4,5-dihydro-1H-benz[g]indazole-3-carboxylate, 100 parts of aqueous 10 percent sodium hydroxide solution and 120 parts of methanol is refluxed and stirred for 3 hours. The mixture is then cooled and acidified with concentrated hydrochloric acid. The solid which forms is separated by filtration, washed with water, and dried to give 7-chloro-1-phenyl-4,5-dihydro-1H-benz[g]indazole-3-carboxylic acid melting at about 282°C. with evolution of gas.

Provenance & Evidence