Methyl iodide → 1,2-dihydro-4,4-dimethyl-9-methoxy-7-(3-methyl-2-octyl)-4H-thieno[2,3-c][1]benzopyran

HRID 1579096Notes

Reaction equation

HRID 1579096 reaction equation
[CH3:1][C:2]1([CH3:25])[C:7]2[S:8][CH2:9][CH2:10][C:6]=2[C:5]2[C:11]([OH:24])=[CH:12][C:13]([CH:15]([CH:17]([CH3:23])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH3:16])=[CH:14][C:4]=2[O:3]1.CI.[O-][CH2:29]C.[Na+]>>[CH3:25][C:2]1([CH3:1])[C:7]2[S:8][CH2:9][CH2:10][C:6]=2[C:5]2[C:11]([O:24][CH3:29])=[CH:12][C:13]([CH:15]([CH:17]([CH3:23])[CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH3:16])=[CH:14][C:4]=2[O:3]1

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 2135232H-Thieno(2,3-c)(1)benzopyran-9-ol, 1,4-dihydro-7-(1,2-dimethylheptyl)-4,4-dimethyl-HCID 2723922Sodium ethoxide

Product 1

HCID 215579131,2-dihydro-4,4-dimethyl-9-methoxy-7-(3-methyl-2-octyl)-4H-thieno[2,3-c][1]benzopyran

Procedure

By reacting 1,2-dihydro-4,4-dimethyl-9-hydroxy-7-(3-methyl-2-octyl)-4H-thieno[2,3-c][1]benzopyran with methyl iodide in the presence of sodium ethoxide, there is obtained 1,2-dihydro-4,4-dimethyl-9-methoxy-7-(3-methyl-2-octyl)-4H-thieno[2,3-c][1]benzopyran.

Sources & evidence

ORD record
ord-1e4064fd93fa418c81fda45ff9b73e22
Source dataset
uspto-grants-1976_02
Patent number
US03940421

Reaction notes

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