Hydrogen Bromide → HCID 12212094, compound

HRID 1579137Notes

Reaction equation

HRID 1579137 reaction equation
[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][N:8]=[CH:9]2)([O-:3])=[O:2].[BrH:14]>C(O)C>[BrH:14].[N+:1]([C:4]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:5]=1[CH:6]=[CH:7][N:8]=[CH:9]2)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 690855-Nitroisoquinoline

Product 1

HCID 12212094HCID 12212094, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

5-nitro-isoquinoline (3 g) was dissolved in warm ethanol (40 ml) and hydrogen bromide was added (4.5 ml of a 48% w/v aqueous solution). The salt precipitated immediately, and the reaction mixture was cooled to room temperature, filtered, the residue washed with ethanol, and dried, to yield 3.95 g of 5-nitro-isoquinoline hydrobromide of melting point 250.5°C.

Workup

  1. customThe salt precipitated immediately
  2. filtrationfiltered
  3. washthe residue washed with ethanol
  4. customdried

Sources & evidence

ORD record
ord-9684207c18314dd8bfb486a55ff3d672
Source dataset
uspto-grants-1976_01
Patent number
US03930837

Reaction notes

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