Acetic Acid → HCID 21567778, compound

HRID 1579160Notes

Reaction equation

HRID 1579160 reaction equation
[C:1]([C:6]1[CH:17]=[CH:16][C:9]2[N:10]3[CH2:15][CH2:14][CH2:13][C:11]3=[N:12][C:8]=2[CH:7]=1)([O:3]CC)=[O:2].C(O)(=O)C>C(O)C.[OH-].[Na+]>[C:1]([C:6]1[CH:17]=[CH:16][C:9]2[N:10]3[CH2:15][CH2:14][CH2:13][C:11]3=[N:12][C:8]=2[CH:7]=1)([OH:3])=[O:2]

Participants

5

Reactant 2

HCID 176Acetic AcidHCID 12493646HCID 12493646, compound

Product 1

HCID 21567778HCID 21567778, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

A solution of 5 g of 6-carbethoxy-2,3-dihydro-1H-pyrrolo [1,2-a]benzimidazole (1A06) in 15 cm3 of ethanol and 25 cm3 of 2,5 N sodium hydroxide are refluxed for 5 min. After cooling the reaction mixture is slightly acidified with diluted acetic acid and the precipitate formed is sucked off and washed with water and ethanol. Yield: 4 g. Melting point: 300°c.

Workup

  1. temperatureAfter cooling the reaction mixture
  2. customthe precipitate formed
  3. washwashed with water and ethanol

Sources & evidence

ORD record
ord-cd4defa30a36408e98e33a802389daba
Source dataset
uspto-grants-1976_01
Patent number
US03931156

Reaction notes

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