Nitromethane → HCID 21568115, compound

HRID 1579215Notes

Reaction equation

HRID 1579215 reaction equation
[Cl:1][C:2]1[C:3]([CH3:17])=[CH:4][C:5]2[C:6]([CH:16]=1)=[C:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[O:8][N:9]=2.[C:18](O)([CH3:21])([CH3:20])[CH3:19].[N+](C)([O-])=O.[F:27][B-:28]([F:31])([F:30])[F:29].[H+]>C(OCC)C>[F:27][B-:28]([F:31])([F:30])[F:29].[C:18]([N+:9]1[O:8][C:7]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[C:6]2[CH:16]=[C:2]([Cl:1])[C:3]([CH3:17])=[CH:4][C:5]=12)([CH3:21])([CH3:20])[CH3:19]

Participants

6

Reactant 4

HCID 6375NitromethaneHCID 6386tert-ButanolHCID 28118Tetrafluoroboric acidHCID 46428025-Chloro-6-methyl-3-phenyl-2,1-benzisoxazole

Product 1

HCID 21568115HCID 21568115, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a suspension of 59 g. of 5-chloro-6-methyl-3-phenyl-2,1-benzisoxazole, 26.6 ml. of tert.-butanol and 740 ml. of nitromethane, is added dropwise 45.7 g. of a 50% aqueous solution of tetrafluoroboric acid. The resulting suspension is stirred at room temperature for 85 hours. The reaction mixture is diluted with approximately 10 liters of diethyl ether and the crystalline precipitate formed is isolated by filtration to yield 1-tert.-butyl-5-chloro-6-methyl-3-phenyl-2,1-benzisoxazolium tetrafluoroborate, m.p. 164°-166°C.

Workup

  1. additionTo a suspension of 59 g
  2. customthe crystalline precipitate formed
  3. customis isolated by filtration

Sources & evidence

ORD record
ord-025b34c086994a9fa69751fb4459f59e
Source dataset
uspto-grants-1976_01
Patent number
US03931172

Reaction notes

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